It also covers side effects, interactions, and what to look for. All rights reserved. Potters Comfrey Oil | Holland & Barrett Shop our range of Potter's Herbals products at Holland & Barrett, including Potters Comfrey Oil. Am J Med 1990;89:547-8. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Therefore, it is important to talk to your healthcare provider about any supplements you plan to take and to check in about any potential interactions with other supplements or medications. Molecules. Comfrey should not be used in place of medication prescribed for you by your doctor. The leaves and stems of comfrey contain pyrrolizidine alkaloids that can cause toxic damage if ingested in excess (Ulbricht, 2010). A systematic review and quality assessment of case reports of adverse events for borage (Borago officinalis), coltsfoot (Tussilago farfara) and comfrey (Symphytum officinale). Symphytum officinale L., dermal use (Flexagile cream)]. 2010;44(9):637-641. 95 ($14.78/Fl Oz) FREE delivery Wed, Mar 8 on $25 of items shipped by Amazon. Comfrey cream combines ingredients like oils or water and glyceryl stearate with Symphytum officinale (comfrey) extracts. Symphytum officinale), store bought or via recipe, above. Wound-healing effects of a symphytum herb extract cream (. Squish and squeeze as many leaves into as you can into the container. Koll, R., Buhr, M., Dieter, R., Petrowicz, O., Gianetti, B., and Wagener, S. Wirksamkeit und Vertraglichkeit von Beinwellextrakt (Extr. Wien.Med.Wochenschr. Phytother Res. Gyorik, S. and Stricker, H. Severe pulmonary hypertension possibly due to pyrrolizidine alkaloids in polyphytotherapy. Complement Ther Med. Br.J Sports Med. Barna, M., Kucera, A., Hladikova, M., & Kucera, M. (2012). Thus, it is not advised to ingest herbal preparations of comfrey unless guided by an expert pharmacologist and physician. Efficacy and safety of comfrey root extract ointment in the treatment of acute upper or lower back pain: Results of a double-blind, randomised, placebo controlled, multicentre trial. Comfrey: Uses, Risks, and Takeaways - Healthline 2013;5(5):CD010538. Latest: Senior Software Engineer - Front End Senior Software Engineer Senior Product Manager - Basket, Checkout and Payments UX Designer - Instore Tech. Select a condition to view a list of vitamins. 2020;142:104519. 2013;21(6):724-745. doi:10.1016/j.ctim.2013.09.009. Drugs and Lactation Database (LactMed). Because of the risk of liver toxicity, comfrey cream shouldn't be used with other medicines that may also cause liver damage. A later study of 133 peoplefound some evidence that a topical combination of comfrey extract and tannic acid led to reduced knee pain. Do not use extra comfrey to make up the missed dose. Verywell Health's content is for informational and educational purposes only. Topically, comfrey root and leaf extracts have been traditionally used for bruises, sore muscles and joints, sprains, mild wounds, and gout (Natural Medicines, 2020). Jedlinszki, N., Balzs, B., Csnyi, E., & Csupor, D. (2017). Call your doctor for medical advice about side effects. View abstract. When harvesting comfrey or buying from a non-commercial supplier, note that there is variety within the species. Comfrey Cream Recipe for Achy Joints and Muscles - Herbal Academy Chojkier M. Hepatic sinusoidal-obstruction syndrome: toxicity of pyrrolizidine alkaloids. Definitely do not use during pregnancy or nursing, with infants, and if you have liver or kidney disease. Herbal medicine for low back pain: A Cochrane review. 2011;10(3):147-56. 2018;19(5):455-474. doi:10.1016/j.jpain.2017.11.005, Gagnier JJ, Oltean H, van Tulder MW, Berman BM, Bombardier C, Robbins CB. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Undergoingmassage or taking up yoga may help alleviate pain and help people with back or joint problems function more easily. The most common over-the-counter medication that can be toxic to the liver is acetaminophen (Tylenol). A symptomatic treatment of minor sprains and bruises. The following applications have been used in research: Using large amounts of comfrey cream or using it for extended periods of time increases the risk of side effects like liver toxicity. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Comfrey cream combines ingredients like oils or water and glyceryl stearate with Symphytum officinale (comfrey) extracts. 211727395. Barthomeuf, C. M., Debiton, E., Barbakadze, V. V., and Kemertelidze, E. P. Evaluation of the dietetic and therapeutic potential of a high molecular weight hydroxycinnamate-derived polymer from Symphytum asperum Lepech. Topical preparations of comfrey are generally safe provided they are not applied excessively or to an open wound. Wound-healing effects of a symphytum herb extract cream (Symphytum uplandicum Nyman) in children: A randomized double-blind study. However, people with knee pain may be glad to try a topical preparation that could help in addition to any other recommendations made by their physician. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. 2 Comfrey cream contains several active components (substances). View abstract. 2017;83:1-4. However, not a rate considered harmful for those with healthy livers.10,11, Masters Degree in Toxicology and BSc Hons in Medical Biochemistry. Comfrey can also contain echimidine, pyrrolizidine alkaloids (PAs), and symphytine, which can damage the liver, are carcinogenic (cancer-causing) and may harm a fetus. You may also consider consulting a practitioner who is trained in the use of herbal/health supplements. 2012;101(4):211-216. (3), 147-156. https://doi.org/10.1016/j.jcm.2011.01.003. It should never be taken by mouth. of India and by a State Level Environment Impact Assessment Authority constituted by Government of India on the recommendations made . Herb & Supplement Guide. Effects of Symphytum ointment on muscular symptoms and functional locomotor disturbances. Preclinical studies suggest that oral comfrey has antiproliferative effects , and a topical formulation showed wound healing properties . Thank you, {{form.email}}, for signing up. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Stewart MJ, Steenkamp V. Pyrrolizidine poisoning: a neglected area in human toxicology. The Effect of Comfrey on Enoxaparin-Induced Bruise in Patients with Acute Coronary Syndrome: A Randomised Clinical Trial. Can a comfrey (Symphytum officianale) root extraction help ease aching joints and muscles? 4.3 4.3 out of 5 stars (225) $19.95 $ 19. Tolerability and effectiveness of an antitrauma cream with comfrey herb extract in pediatric use with application on intact and on broken skin. To make this recipe, first, you must prepare the comfrey root tincture. Healthy adults: massage about 1 teaspoon of cream into a local area up to 4x/day for up to 2 weeks. Can comfrey be used for cracked nipples during breastfeeding? 12 drops peppermint (Mentha piperita) essential oil Journal of chiropractic medicine, 10(3), 147-156. https://doi.org/10.1016/j.jcm.2011.01.003, Stam, C., Bonnet, M. S., & van Haselen, R. A. Symphyti) in the treatment of ankle distorsions: results of a multicenter, randomized, placebo-controlled, double-blind study. Mix for about 10 minutes, until nice and whipped. What are the benefits of using it? Comfrey (Symphytum officinale) is a plant with yellow or purple flowers found in Europe, Asia, and North America. British journal of sports medicine, 44(9), 637-641. https://doi.org/10.1136/bjsm.2009.058677, Grube, B., Grnwald, J., Krug, L., & Staiger, C. (2007). reduce lower back pain (Stam et al., 2001). Wichtl, M. (2004). Contact your doctor or pharmacist if you have any questions before use. For that reason, Ive also included my go-to comfrey cream recipe for achy joints and muscles! Shop buy 1 get 1 half price on all gut health products, Buy 1 get 1 Half Price | Plus an extra 20% off 25, App Exclusive | Get an extra 22% off 25 when you spend on the H&B App, Royal Mail strikes may cause a delay to our click and collect service, Looking for fitness advice & inspiration this New Year? Using different formulations together increases the risk of an overdose. Pour into bowl /jug big enough for all ingredients and safe for the mixer. This includes androstenedione, bishop's weed, borage, chaparral, comfrey, DHEA, echinacea, garlic, germander, golden ragwort, hound's tongue, kava, licorice, niacin (vitamin B3), pennyroyal oil, red yeast, St. John's wort, and others. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Make sure to always buy comfrey (Symphytum officianale) root and leaf from a trusted source. radix) extract ointment in the treatment of patients with painful osteoarthritis of the knee: Results of a double-blind, randomised, bicenter, placebo-controlled trial. Limited trials have evaluated the effectiveness of alkaloid-free preparations for external use; however, these studies did not examine how much liver damage occurred in patients. She is passionate about providing evidence-based recommendations that make health decisions easier and improve lives. Safety Alerts & Advisories: FDA Advises Dietary Supplement Manufacturers to Remove Comfrey Products From the Market. In Western Europe, comfrey has been used topically for treating inflammatory disorders such as arthritis, gout, and thrombophlebitis, and internally for treating diarrhea. Call your doctor for medical advice about . A handbook for practice on a scientific basis. comfrey cream holland and barrett - daxasys.com 1 It's found in Europe, Asia, and North America. of India has issued Environment Impact Assessment EIA Notification dated 14th September, 2006 for according Environment Clearance(EC) to 8 categories of industries/projects by the Ministry of Environment & Forests, Govt. Do not take comfrey without medical advice if you are using any of the following medications: This list is not complete. Comfrey. Roeder E. Medicinal plants in Europe containing pyrrolizidine alkaloids. HTB; 2021 2; Youtube; Twitter; Facebook; ; 2013;163(3-4):58-64. View abstract. Comfrey has been cultivated as a green vegetable and has been used as an herbal medicine for more than 2,000 years. Copyright 1996-2023 Cerner Multum, Inc. Skin patch test before use, especially if you have sensitive skin, and never use on a deep wound. Predel, H. G., Giannetti, B., Koll, R., Bulitta, M., & Staiger, C. (2005). View abstract. In 2001, the Food and Drug Administration (FDA) banned oral comfrey products. (2013). If you choose to use comfrey, use it as directed on the package or as directed by your doctor, pharmacist, or other healthcare provider. It also came as a reference to the belief that comfrey can mend broken bones. Influence of moderate physical exertion on subacute low back pain, after Symphytum officinale ointment treatment. Phytomedicine. 20 Rewards for Life points with this purchase, Potters Herbals Comfrey Ointment is a traditional herbal medicinal product used for the symptomatic relief of minor sprains and bruises, based on traditional use only. Safety Alerts & Advisories: FDA Advises Dietary Supplement Manufacturers to Remove Comfrey Products From the Market. The recipe makes about 5 cups of whipped creamy lotion. Choose organically grown comfrey when possible. Although it has historically been used on open wounds, it is now not advised related to the toxic pyrrolizidine alkaloids that can absorb more readily into the body through an open wound. Although not all side effects are known, comfrey is thought to be possibly safe when applied to unbroken skin for less than 10 days. Phytomedicine, 12(10), 707-714. https://doi.org/10.1016/j.phymed.2005.06.001, Smith, D. B., & Jacobson, B. H. (2011). Book your free, one-to-one online consultation with one of our qualified advisors. Allow the oil mixture to cool until it reaches room temperature, which could take 8-12 hours. A few studies show that comfrey cream may be helpful in the treatment of ankle sprains. It should only be used in small amounts for short periods as a cream. Simply massage into the skin as required. 1 Since at least the 4 th century, people have used comfrey medicinally. View abstract. Tunon, H., Olavsdotter, C., and Bohlin, L. Evaluation of anti-inflammatory activity of some Swedish medicinal plants. hollandandbarrett.com is a trading name of Holland & Barrett Retail Limited,. Tanret, I. and Duh, D. [Pharmaceutical sheet. The leaves and stems of comfrey contain pyrrolizidine alkaloids that can cause toxic damage if ingested in excess (Ulbricht, 2010). To Use. Other drugs may interact with comfrey, including prescription and over-the-counter medicines, vitamins, and herbal products. COMFREY: Overview, Uses, Side Effects, Precautions - WebMD Without overexposure to air or heatand without cross-contaminationthe recipe should last as long as the expiration date of the carrier oils used. 2012;(1):41-42. Efficacy and safety of comfrey root extract ointment in the treatment of acute upper or lower back pain: Results of a double-blind, randomised, placebo controlled, multicentre trial. When the root is boiled in water, it forms a sticky, glue-like paste. Potters Herbal Comfrey Oil is a soothing aromatic herbal massage oil. (10), 707-714. https://doi.org/10.1016/j.phymed.2005.06.001. Comfrey has also been used for the following conditions: There is currently not enough evidence to recommend comfrey cream for any of these uses. By Megan Nunn, PharmD Comfrey Cream: Uses, Benefits, Side Effects, Dosage - Verywell Health Wang YP, Yan J, Fu PP, Chou MW. Satisfaction. Two interesting studies found that a topical application of a product containing comfrey root extract helped with knee pain and stiffness. A significant reduction in pain was observed in the groups using the comfrey product. Maryland Heights, MO. Credit Solution Experts Incorporated offers quality business credit building services, which includes an easy step-by-step system designed for helping clients build their business credit effortlessly. When considering the use of herbal supplements, seek the advice of your doctor. Our associates are qualified to advise, visit us online or in store for unparalleled advice. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you. View abstract. This is the tincture. Whether you are treated by a medical doctor or a practitioner trained in the use of natural medicines/supplements, make sure all your healthcare providers know about all of your medical conditions and treatments. Frost R, O'meara S, Macpherson H. The external use of comfrey: a practitioner survey. Efficacy of a comfrey root (Symphyti offic. The study involved 43 patients with knee osteoarthritis and a six-week treatment period. 2007;14(1):2-10. Hybrids and other species may have a similar appearance but could have significantly different amounts of the toxic pyrrolizidine alkaloids (Kucera et al., 2018). Drug class: Herbal products. Comfrey has been used in alternative medicine as a possibly effective aid in treating back pain, osteoarthritis, or tenderness and swelling caused by a sprain injury. Lorem ipsum dolor sit nulla or narjusto laoreet onse ctetur adipisci. Thus, it is not advised to ingest herbal preparations of comfrey unless guided by an expert pharmacologist and physician. Comfrey may have been applied to the skin in a specific preparation to treat some of these conditions. Whether youre familiar with it or not, this unusual herbal remedy is definitely worth knowing more about. Pharmazie 1995;50:83-98. HOLLAND & BARRETT PRO VITAMIN E DAY CREAM 50ML This Vitamin E day cream works with your skin daily to hydrate and protect your skin. WebMD does not provide medical advice, diagnosis or treatment. Additionally, because its alkaloids are absorbed through the skin, use of comfrey as a poultice should not exceed an exposure of 100 mcg/day of the alkaloids. 2004;11(6):470-477. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed. After testing their 1000mg CBD oil drops for over a month, we now have little question this is the best CBD oil within the UK as of 2019. In Western Europe, comfrey has been used topically for treating inflammatory disorders such as arthritis, gout, and thrombophlebitis, and internally for treating diarrhea. (21), 498-507. https://link.springer.com/article/10.1007/s10354-004-0114-8, Natural Medicines (2020). Other uses not proven with research have included skin wounds, skin ulcers, cough, sore throat, gum disease, joint pain, diarrhea, and other conditions. Lewis, C. J. FDA Advises Dietary Supplement Manufacturers to Remove Comfrey Products From the Market. (2001). To make the cream, combine sunflower oil, safflower oil, coconut oil, and cocoa butter in a double-boiler over low heat until completely melted. Treatment with 4Jointz reduces knee pain over 12 weeks of treatment in patients with clinical knee osteoarthritis: a randomised controlled trial. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use. Its ready when the mixture has solidified somewhat and has a cloudy, creamy, and slightly runny consistency. They help us to understand how people use the website and give us the ability to provide targeted marketing to you. Results of an observational study of patients]. It is called knitbone or boneset, referring to the bone-like growth of its roots. Consult your healthcare provider before using comfrey cream. Electric bowl mixer (like a KitchenAid) or a blender, Small glass jars with lids for sharing (optional). hollandandbarrett.com is a trading name of Holland & Barrett Retail Limited,. Inhibition of prostaglandin biosynthesis and PAF-induced exocytosis. Drug-induced liver injury. Topical preparations of comfrey are generally safe provided they are not applied excessively or to an open wound. As a Licensed Massage Therapist for fifteen years, I have noticed that back pain can be caused by a variety of reasons and can be very debilitating. No comments. When buying commercial brands, seek those that have had the pyrrolizidine alkaloids removed, if possible. Symphytum officinale L, S. asperum Lepechin, S. tuberosum L, Symphytum x uplandicum Nyman. Retrieved from, https://naturalmedicines.therapeuticresearch.com/databases/food,-herbs-supplements/professional.aspx?productid=295. Some drugs increase how quickly the liver changes and breaks down comfrey. Effect of a blend of comfrey root extract (Symphytum officinale L.) and tannic acid creams in the treatment of osteoarthritis of the knee: randomized, placebo-controlled, double-blind, multiclinical trials. Acupuncture for Chronic Pain: Update of an Individual Patient Data Meta-Analysis. J Agric.Food Chem 2001;49(8):3942-3946. A review of 26 clinical trials concluded that mild skin reactions were the most common side effects of comfrey creams used in the studies. Avoid with medications that induce CYP3A4 or are hepatotoxic (Natural Medicines, 2020). Comfreycontains PAs, substances that can cause significant damage, including: Therefore, it should never be taken by mouth. Rad. MedlinePlus Medical Encyclopedia. Topically applied comfrey oil is associated with a wide range of health benefits and can help with certainissues including: Comfrey oil is good at helping with superficial cuts, scratches, and scrapes. This is done by soaking the root in at least 50% alcohol for a minimum of two weeks. Barna, M., Kucera, A., Hladicova, M., and Kucera, M. [Wound healing effects of a Symphytum herb extract cream (Symphytum x uplandicum NYMAN: ): results of a randomized, controlled double-blind study]. 2010;13(7-8):509-526. doi:10.1080/10937404.2010.509013, Staiger C. Comfrey: A clinical overview. If your healthcare provider recommends it, make sure to use it on intact skin for a small amount of time, and be careful that infants do not ingest it.